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NEET2005ChemistryBiomoleculesActual

Which functional group participates in disulphide bond formation in proteins?

Options

  1. AThioester
  2. BThioether
  3. CThiol
  4. DThiolactone

Correct answer

C. Thiol

Step-by-step solution

A disulfide bond is a covalent bond between two sulfur atoms (-S-S-) formed by the coupling of two thiol (-SH) groups. Related Theory In the mammalian endoplasmic reticulum (ER), disulfide bond formation is achieved by the combined action of two types of enzyme: one capable offorming disulfides de novo and another able to introduce these disulfides into substrates.

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