NEET2026ZoologyBiotechnology and Its ApplicationsActual
The inactive form of Bt toxin is converted to the active form in the insect gut __________.
Options
- Aby nucleases
- Bdue to alkaline pH
- Cdue to acidic pH
- Dby proteases
Correct answer
B. due to alkaline pH
Step-by-step solution
Bt toxin is produced by the bacterium Bacillus thuringiensis in an inactive form called protoxin. When an insect ingests this inactive toxin, it enters the gut where the pH is alkaline. The alkaline pH of the insect gut solubilizes the protein crystals, converting the inactive protoxin into its active form. The active toxin then binds to the surface of midgut epithelial cells, creating pores that cause cell swelling and lysis, eventually leading to the death of the insect. Answer: due to alkaline pH