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NEET 2020
Exam
NEET
Year
2020
Subject
Zoology
Chapter
Body Fluids and Circulation

NEET 2020 · Zoology · Body Fluids and Circulation

Which of the following conditions cause erythroblastosis foetalis?

Which of the following conditions cause erythroblastosis foetalis?

Options

  1. AMother Rh+ve{Rh}^{+ \text{ve}} and foetus Rh−ve{Rh}^{- \text{ve}}
  2. BMother Rh−ve{Rh}^{- \text{ve}} and foetus Rh+ve{Rh}^{+ \text{ve}}
  3. CBoth mother and foetus Rh−ve{Rh}^{- \text{ve}}
  4. DBoth mother and foetus Rh+ve{Rh}^{+ \text{ve}}

Correct answer

B. Mother Rh−ve{Rh}^{- \text{ve}} and foetus Rh+ve{Rh}^{+ \text{ve}}

Step-by-step solution

A special case of RhRh incompatibility (mismatching) has been observed between the Rh−ve{Rh}^{- ve} blood of a pregnant mother with Rh+ve{Rh}^{+ ve} blood of the foetus. The Rh−ve{Rh}^{- ve} mother is not usually exposed to the RhRh antigen of the foetus during the first pregnancy as the foetal and maternal blood are normally kept well separated by the placental barriers. However, at the time of the birth of the first child, there is a possibility of exposure of the maternal blood to a small amount of Rh+ve{Rh}^{+ ve} blood from the foetus. Hence, the body of the mother starts preparing antibodies against RhRh antigens in her blood.

These antibodies (a type of IgGIgG antibody) could cross the placental barriers in subsequent pregnancies and cause haemolysis of the Rh+ve{Rh}^{+ ve} red blood cells of the foetus. This could be fatal to the foetus or could cause severe anaemia and jaundice to the baby (HDNHDN- a haemolytic disease of newly born). This condition is called erythroblastosis fetalis.

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