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NEET2010ZoologyExcretory Products and their EliminationActual

The principal nitrogenous excretory compound in humans is synthesised

Options

  1. Ain kidneys but eliminated mostly through liver
  2. Bin kidneys as well as eliminated by kidneys
  3. Cin liver and also eliminated by the same through bile
  4. Din the liver, but eliminated mostly through kidneys

Correct answer

D. in the liver, but eliminated mostly through kidneys

Step-by-step solution

In humans, the principal nitrogenous excretory compound (ie, urea) is synthesized in liver by ornithine cycle. In liver, one molecule of CO ₂ is activated by biotin and combines with two molecules of NH ₃ in the presence of carbamyl phosphate synthetase enzyme and 2ATP to form carbamyl phosphate and one molecule of H ₂ O is released. Carbamyl phosphate reacts with ornithine and forms citrulline. Citrulline combines with another molecule of ammonia and form arginine that is broken into urea and ornithine in the pres

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