NEET2017ZoologyMolecular Basis of InheritanceActual
During DNA replication, Okazaki fragments are used to elongate:
Options
- AThe leading strand towards replication fork
- BThe lagging strand towards replication fork
- CThe leading strand away from replication fork
- DThe lagging strand away from the replication fork
Correct answer
D. The lagging strand away from the replication fork
Step-by-step solution
The DNA polymerase III molecule helps in the DNA fork to synthesize simultaneously the DNA. One of the strands, with proper orientation, functions as a leading strand for which the synthesis is continuous. The lagging strand is oppositely oriented and thus, DNA Pol-III synthesizes this in fragments called the Okazaki fragment. Each Okazaki fragment is synthesized by DNA polymerase at lagging strand in 5 ′ → 3 ′ direction. New Okazaki fragments appear as the replication fork opens further. As the f