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NEET 2017
Exam
NEET
Year
2017
Subject
Zoology
Chapter
Molecular Basis of Inheritance

NEET 2017 · Zoology · Molecular Basis of Inheritance

During DNA replication, Okazaki fragments are used to elongate:

During DNA replication, Okazaki fragments are used to elongate:

Options

  1. AThe leading strand towards replication fork
  2. BThe lagging strand towards replication fork
  3. CThe leading strand away from replication fork
  4. DThe lagging strand away from the replication fork

Correct answer

D. The lagging strand away from the replication fork

Step-by-step solution

The DNA polymerase III molecule helps in the DNA fork to synthesize simultaneously the DNA. One of the strands, with proper orientation, functions as a leading strand for which the synthesis is continuous. The lagging strand is oppositely oriented and thus, DNA Pol-III synthesizes this in fragments called the Okazaki fragment. Each Okazaki fragment is synthesized by DNA polymerase at lagging strand in 5′→3′{5}^{′} \to {3}^{′} direction. New Okazaki fragments appear as the replication fork opens further.

As the first Okazaki fragment appears away from the replication fork, the direction of elongation would be away from replication fork.
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