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NEET2019ZoologyMolecular Basis of InheritanceActual

Under which of the following conditions will there be no change in the reading frame of the following mRNA? 5'AACAGCGGUGCUAUU 3'

Options

  1. AInsertion of G at 5 t h position
  2. BDeletion of G from 5 t h position
  3. CInsertion of A and G at 4 t h and 5 t h positions respectively
  4. DDeletion of GGU from 7 t h 8 t h and 9 t h positions

Correct answer

D. Deletion of GGU from 7 t h 8 t h and 9 t h positions

Step-by-step solution

Genetic codes are read in the sequence of 3. Insertion or deletion of a single base changes the reading frame of codon and is called frameshift mutation. However, insertion or deletion of three or its multiple bases insert or delete in one or multiple codon hence one or multiple amino acids and reading frame remains unaltered from that point onwards.

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