NEET2009ZoologyMolecular Basis of InheritanceActual
Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a triplet?
Options
- ANirenberg and Mathaei
- BHershey and Chase
- CMorgan and Sturtevant
- DBeadle and Tatum
Correct answer
A. Nirenberg and Mathaei
Step-by-step solution
The existence of triplet code was simply an assumption till 1961, when Nirenberg and Methaei proved its existence by experiments. They were able to synthesize artificial mRNA, which contained only one nitrogenous base, ie, uracil. This synthetic poly U sequence was then placed in a cell free system containing protein synthesizing enzymes (extracted from bacterium E. coli) and 20 amino acids together with necessary ATP. During the process, a small polypeptide molecule was produced, which was formed by the linking of