NEET2008ZoologyMolecular Basis of InheritanceActual
What is antisense technology?
Options
- AA cell displaying a foreign antigen used for synthesis of antigens.
- BProduction of somaclonal variants in tissue cultures.
- CWhen a piece of RNA that is complementary in sequence is used to stop expression of a specific gene
- DRNA polymerase producing DNA
Correct answer
C. When a piece of RNA that is complementary in sequence is used to stop expression of a specific gene
Step-by-step solution
The antisense RNA technology simply involves the synthesis of RNA molecules that are complementary to the mRNA molecules produced by transcription of a given gene. Usually this antisense RNA will not contain the regulatory sequences required for translation but even if it does it will not usually specify a functional product. Instead most antisense RNAs contain multiple termination codons in all three reading frames. However, when antisense RNA molecules are present in the same cytosol with sense (mRNA) molecules o