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NEET 2023
Exam
NEET
Year
2023
Subject
Zoology
Chapter
Principles of Inheritance and Variation

NEET 2023 · Zoology · Principles of Inheritance and Variation

In which disorder change of single base pair in the gene for beta...

In which disorder change of single base pair in the gene for beta globin chain results in change of glutamic acid to valine?

Options

  1. AHaemophilia
  2. BPhenylketonuria
  3. CThalassemia
  4. DSickle cell anaemia

Correct answer

D. Sickle cell anaemia

Step-by-step solution

Sickle-cell anaemia is caused by mutation of the gene controlling β\beta-chain of haemoglobin. Due to this mutation, glutamic acid present at 6th 6^{\text{th }} position of the β\beta-chain is replaced by amino acid valine.
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