NEET2003ZoologyPrinciples of Inheritance and VariationActual
Which one of the following conditions though harmful in itself, is also potential saviour from a mosquito borne infectious disease?
Options
- Athalassaemia
- Bsickle cell anaemia
- Cpernicious anaemia
- Dleukaemia
Correct answer
B. sickle cell anaemia
Step-by-step solution
Sickle cell anaemia is a genetic disorder caused by a variant form of haemoglobin in red blood cells. Individual homozygous for this disorder die at an early stage. In heterozygotes also the redblood cells with variant form of haemoglobin become sickle-shaped and were unable to bind oxygen efficiently. Even then the natural selection could not eliminate this abnormal allele from the population. This variant is often found in tropical Africa where malaria is common. Since sickle-shaped RBC effectively kills the mala