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NEST2020BiologyBiomolecules (B)

Monomeric subunits of proteins can sometimes assemble into higher order assemblies. Two such related human proteins P and Q assemble into hexamers by sequential assembly of their subunits. However, while P assembles into a hexameric ring, Q assembles into a linear hexameric arrangement as shown in the figure. Only hexameric assemblies of the proteins are functional. The equilibrium constants for association (K₁, K₂,

Options

  1. AFor Q , G ^ at the final step of assembly is half as much as the earlier step.
  2. BCellular concentration of Q must be higher than that of P .
  3. CFor all steps in assembling P and Q , G ^ remains the same.
  4. DFor P , G ^ at the final step of assembly is twice that of the earlier step.

Correct answer

D. For P , G ^ at the final step of assembly is twice that of the earlier step.

Step-by-step solution

No solution available.

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