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NEST2021BiologyCell Cycle and Cell Division

Compared to differentiated cells, stem cells have a longer interphase. Three different human alveolar cell-types (stem cells, normal cells and cancer cells) grown under optimal laboratory conditions were examined microscopically (Figure). The nucleus was stained blue and phos-H2A.X protein green. Phos-H2A.X is found only at damaged DNA site in vivo. Each green dot is considered as an event of DNA damage or a cluster

Options

  1. AAlthough carcinogens damage DNA, cellular processes do not lead to such damages.
  2. BThe rate of cell division can be directly correlated to the number of DNA breaks.
  3. CThe experiment clearly indicates that the M-phase of the three cell types is different.
  4. DThe rate of DNA damage is inversely proportional to its occurrence in cancer cells.

Correct answer

B. The rate of cell division can be directly correlated to the number of DNA breaks.

Step-by-step solution

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