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NEST2014BiologyPrinciples of Inheritance and Variation

Huntington's disease is a genetic disorder that leads to defects in brain function and is always fatal. The affected gene consists of a sequence of DNA having multiple repeats of the nucleotide sequence CAG. A factor that determines whether an allele of this gene causes Huntington's disease or not is the number of CAG repeats. The graph on the right shows the age (in years) at which patients (each represented by a do

Options

  1. AThere could be factors other than number of CAG repeats that determine the age of onset.
  2. BThere is a negative correlation between age of onset and number of CAG repeats.
  3. CHuntington's disease is fatal and is therefore not heritable.
  4. DHuntington's disease is heritable and can be passed onto offspring.

Correct answer

D. Huntington's disease is heritable and can be passed onto offspring.

Step-by-step solution

No solution available.

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