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NEST2020ChemistryAldehydes and Ketones

Carbanions derived from aldehydes/ketones are called enolates, as they represent anions (conjugate bases) of the enol forms. Enol ethers can be prepared and are synthetically important. These anions react with an alkyl halide at the carbon or oxygen atom. Trimethylsilylchloride ( Me ₃ SiCl ) reacts almost exclusively with enolates. One such reaction is shown below, where ketone I is treated with LDA , followed by Me

Options

  1. AIII is more stable than II.
  2. BThe activation energy for the formation of IV is lower than that of VI.
  3. CIn the conversion of IV to VIII, CH ₃ Li function as a nucleophile.
  4. DThe activation energy for the formation of II is lower than that of III.

Correct answer

D. The activation energy for the formation of II is lower than that of III.

Step-by-step solution

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