To study any kind of genetic abnormality arising due to change is chromosome number, the karyotype is prepared. Which of the following stages is most suitable to develop a karyotype?

Step-by-step solution

A karyotype is a profile of organisms chromosomes that are organized by their size, pattern, and location of centromere. Chromosomes are most distinct in the metaphase stage. In the telophase stage, they regain their coiled composition. In anaphase, the chromatids separate and move towards opposite poles. In the prophase stage, the chromosomes appear thread-like and individual chromatids cannot be seen.