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NTA Abhyas NEET2020ChemistryBiomoleculesPractice

Which of the following statement is correct about competitive inhibitors?

Options

  1. AThe inhibitor does not resembles the substrate.
  2. BThe inhibitor competes with the substrate for the allosteric sites.
  3. CInhibition of succinic hydrogenase by malonate which doesn't resemble the substrate succinate in structure is
  4. DThis mechanism is used in the control of bacterial pathogens.

Correct answer

D. This mechanism is used in the control of bacterial pathogens.

Step-by-step solution

When the inhibitor closely resembles the substrate in its molecular structure and inhibits the activity of the enzyme, it is known as a competitive inhibitor. Due to its close structural similarity with the substrate, the inhibitor competes with the substrate for the substrate-binding site of the enzyme. Consequently, the substrate cannot bind and as a result, the enzyme action declines, e.g., inhibition of succinic dehydrogenase by malonate which closely resembles the substrate succinate in structure. Such competi

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