NTA Abhyas NEET2020ChemistryBiomoleculesPractice
Which of the statement is true regarding Km?
Options
- AIt is the measure of the stability of the ES complex
- BIt is the measure of the stability of the affinity of an enzyme for its substrate
- CA high Km indicates weak substrate binding
- DAll of these
Correct answer
D. All of these
Step-by-step solution
Michaelis and Menten (1913) introduced a constant Km (Michaelis constant). It is a mathematical derivative or constant which indicates the substrate concentration at which the chemical reaction catalyzed by an enzyme attains half its maximum velocity (Vmax). Km indicates the affinity of the enzyme for its substrate.