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NTA Abhyas NEET2020ChemistryBiomoleculesPractice

Malic acid inhibits the activity of enzyme succinate dehydrogenase. During this inhibition

Options

  1. AV max increases, K m decreases
  2. BV max remains the same, K m decreases
  3. CV max decreases, K m increases
  4. DV max remains the same, K m increases

Correct answer

D. V max remains the same, K m increases

Step-by-step solution

Any substance that can diminish the velocity of an enzyme is known as an inhibitor. The two main types of inhibition are competitive, non-competitive. In competitive inhibition, the enzyme and inhibitor compete to bind to the same active site. Hence if substrate concentration is increased the chances of substrate binding to the enzyme will increase. Thus if (S) increases K m (Michaelis constant) also increases. In non-competitive inhibition, the substrate and inhibitor bind at different sites hence do not compete w

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