NTA Abhyas NEET2020ChemistryBiomoleculesPractice
Which one of the following statements regarding enzyme inhibition is correct?
Options
- ACompetitive inhibition is seen when a substrate competes with an enzyme for binding to an inhibitor protein.
- BCompetitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme.
- CNon-competitive inhibition of an enzyme can be overcome by adding a large amount of substrate.
- DNon-competitive inhibitors bind at the active site on the enzyme surface.
Correct answer
B. Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme.
Step-by-step solution
Competitive inhibition is a reversible inhibition where inhibitor competes with the substrate for the active site of an enzyme. A competitive inhibitor is usually chemically similar to the substrate and therefore, fits into the active site of an enzyme and binds with it. The inhibition is thus due to substrate analogue. The enzyme, now cannot act upon the substrate and reaction products are not formed. Hence, the action of an enzyme may be reduced or inhibited. Since a competitive inhibitor occupies the site only t