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NEETChemistryAmines

A primary amine, RNH 2 can be reacted with CH 3 —X to get secondary amine, R—NHCH 3 but the only disadvantage is that 3° amine and quaternary ammonium salts are also obtained as side products. Is any method possible where RNH 2 forms only 2° amine?

Options

  1. APerform the reaction under high pressure to favor the formation of secondary amines.
  2. BUse a large excess of CH 3 —X to drive the reaction toward the formation of secondary amines.
  3. CCarbylamine reaction is shown by 1° amine only which results in the replacement of two hydrogen atoms attached
  4. DConduct the reaction at a low temperature to favor the formation of secondary amines.

Correct answer

C. Carbylamine reaction is shown by 1° amine only which results in the replacement of two hydrogen atoms attached

Step-by-step solution

Correct Option is : (C) Carbylamine reaction is shown by 1° amine only which results in the replacement of two hydrogen atoms attached to the nitrogen atom of the NH 2 group by one carbon atom. On catalytic reduction the isocyanide will give a secondary amine with one methyl group.

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