NEETChemistryAmines
Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A) : Gabriel phthalimide synthesis is preferred over ammonolysis of alkyl halides for the preparation of pure primary aliphatic amines. Reason (R) : Ammonolysis of alkyl halides involves consecutive nucleophilic substitution reactions leading to a complex mixture of primary, secondary, tertiary amines
Options
- ABoth (A) and (R) are correct and (R) is the correct explanation of (A)
- BBoth (A) and (R) are correct but (R) is not the correct explanation of (A)
- C(A) is correct but (R) is not correct
- D(A) is not correct but (R) is correct
Correct answer
A. Both (A) and (R) are correct and (R) is the correct explanation of (A)
Step-by-step solution
Assertion (A) is correct. Gabriel phthalimide synthesis is a highly useful method for the preparation of pure primary aliphatic amines because it avoids over-alkylation and yields exclusively primary amines. Reason (R) is also correct and provides the exact explanation for the assertion. Ammonolysis of alkyl halides is a nucleophilic substitution reaction where the primary amine formed acts as a nucleophile and further reacts with the alkyl halide. This consecutive reaction leads to a complex mixture of primary, se