- Exam
- NEET
- Subject
- Zoology
- Chapter
- Biotechnology and Its Applications
NEET · Zoology · Biotechnology and Its Applications
Is there a need for mass production of insulin if bacterium can...
Options
- AYes
- BNo
- CMay be
- DThe need depends on various factors
Correct answer
A. Yes
Step-by-step solution
Management of adult-onset diabetes is possible by taking insulin at regular time intervals. What would a diabetic patient do if enough human- insulin was not available? If you discuss this, you would soon realise that one would have to isolate and use insulin from other animals. Would the insulin isolated from other animals be just as effective as that secreted by the human body itself and would it not elicit an immune response in the human body? Now, imagine if bacterium were available that could make human insulin. Suddenly the whole process becomes so simple. You can easily grow a large quantity of the bacteria and make as much insulin as you need. Think about whether insulin can be orally administered to diabetic people or not. Why? Insulin used for diabetes was earlier extracted from pancreas of slaughtered cattle and pigs. Insulin from an animal source, though caused some patients to develop allergy or other types of reactions to the foreign protein. Insulin consists of two short polypeptide chains: chain A and chain B, that are linked together by disulphide bridges