NEETZoologyBiotechnology and Its Applications
Read the following statements and choose the correct option: 1. Gene therapy is a collection of methods that allows correction of a gene defect that has been diagnosed in a child/embryo. 2. Correction of a genetic defect involves delivery of a normal gene into the individual or embryo to take over the function of and compensate for the non functional gene. 3. The first clinical gene therapy was given in 1997 to a 4-y
Options
- Aonly 1 is correct
- BOnly 3 is incorrect
- CBoth 1 and 2 are correct
- DAll are incorrect
Correct answer
B. Only 3 is incorrect
Step-by-step solution
The first clinical gene therapy was given in 1990 to a 4-year old girl with adenosine deaminase (ADA) deficiency. In some children ADA deficiency can be cured by bone marrow transplantation; in others it can be treated by enzyme replacement therapy, in which functional ADA is given to the patient by injection. But the problem with both of these approaches that they are not completely curative. As a first step towards gene therapy, lymphocytes from the blood of the patient are grown in a culture outside the body. A