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NEETZoologyBiotechnology and Its Applications

In eukaryotic cells, mobile genetic elements (transposons) that replicate via an RNA intermediate can act as a natural trigger for a specific cellular defense mechanism. Which of the following molecular processes is directly prevented from occurring by this defense mechanism?

Options

  1. ATranscription of the target gene
  2. BReplication of the transposon DNA
  3. CTranslation of specific mRNA
  4. DSplicing of heterogenous nuclear RNA (hnRNA)

Correct answer

C. Translation of specific mRNA

Step-by-step solution

Transposons that replicate via an RNA intermediate provide a natural source of complementary RNA. This complementary RNA binds to a specific target mRNA, forming double-stranded RNA (dsRNA). The formation of dsRNA initiates RNA interference (RNAi), which is a method of cellular defense in all eukaryotes. The binding of dsRNA specifically prevents the translation of the mRNA into a protein. This process is known as post-transcriptional gene silencing. Therefore, the defense mechanism directly halts translation, not

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