NEETZoologyBiotechnology and Its Applications
A patient undergoes gene therapy to receive a functional gene for the enzyme adenosine deaminase (ADA). The deficiency of this specific enzyme severely compromises which of the following physiological systems in the patient?
Options
- AImmune system
- BRespiratory system
- CDigestive system
- DNervous system
Correct answer
A. Immune system
Step-by-step solution
Adenosine deaminase (ADA) is an enzyme that is crucial for the immune system to function. Its deficiency leads to a disorder where the immune system is severely compromised, making the patient highly susceptible to infections. Gene therapy is attempted to provide a functional ADA gene to the patient's lymphocytes. The respiratory system, digestive system, and nervous system are incorrect because ADA deficiency specifically impairs lymphocyte function and immune responses. For example, respiratory issues like emphys