Read the following statements regarding Adenosine deaminase (ADA) deficiency and its treatments: (a) The ADA enzyme is crucial for the immune system to function. (b) The disease can be completely cured by enzyme replacement therapy. (c) Functional ADA cDNA is introduced into the patient's lymphocytes using a retroviral vector. (d) The genetically engineered lymphocytes injected into the patient are immortal. How many

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Statement (a) is correct as the ADA enzyme is essential for the proper functioning of the immune system. Statement (b) is incorrect because enzyme replacement therapy and bone marrow transplantation are not completely curative. Statement (c) is correct as a retroviral vector is used to introduce functional ADA cDNA into the lymphocytes grown in culture. Statement (d) is incorrect because the genetically engineered lymphocytes are not immortal, which is why the patient requires periodic infusions of these cells. The