NEET 2026
- Exam
- NEET
- Year
- 2026
- Subject
- Biology
- Chapter
- Chapter
NEET 2026 · Biology · Chapter
During the artificial synthesis of human insulin by Eli Lilly, the...
During the artificial synthesis of human insulin by Eli Lilly, the A and B chains were produced separately and extracted. Which type of linkage was artificially created between these extracted chains to form active mature insulin?
Options
- APhosphodiester bond
- BDisulfide bond
- CGlycosidic bond
- DPeptide bond
Correct answer
B. Disulfide bond
Step-by-step solution
In 1983, Eli Lilly, an American company, prepared two DNA sequences corresponding to the A and B chains of human insulin and introduced them into plasmids of E. coli to produce insulin chains.
Chains A and B were produced separately, extracted, and combined by creating disulfide bonds to form active mature human insulin.
Therefore, the linkage artificially created between the extracted chains is the disulfide bond.
Answer: Disulfide bond
Chains A and B were produced separately, extracted, and combined by creating disulfide bonds to form active mature human insulin.
Therefore, the linkage artificially created between the extracted chains is the disulfide bond.
Answer: Disulfide bond