Consider the following statements regarding the production of genetically engineered insulin: (a) The main challenge for the production of insulin using rDNA techniques was getting insulin assembled into a mature form. (b) An American company, Eli Lilly, prepared three DNA sequences corresponding to A, B, and C chains of human insulin. (c) The DNA sequences were introduced into plasmids of E. coli to produce insulin

Step-by-step solution

Statement (a) is correct. The main challenge for the production of insulin using rDNA techniques was getting insulin assembled into a mature form, as natural human insulin is synthesized as a prohormone containing an extra C-peptide which is removed during maturation. Statement (b) is incorrect. In 1983, Eli Lilly, an American company, prepared two DNA sequences corresponding to the A and B chains of human insulin, not the C chain. Statement (c) is correct. The DNA sequences for the A and B chains were introduced i