NEET2026BiologyChapterActual
Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A) : Glucagon interacts with membrane-bound receptors and does not enter the target liver cells. Reason (R) : Glucagon acts on hepatocytes to stimulate glycogenolysis, resulting in an increased blood sugar level. In the light of the above statements, choose the most appropriate answer from the options
Options
- ABoth (A) and (R) are correct and (R) is the correct explanation of (A)
- BBoth (A) and (R) are correct but (R) is not the correct explanation of (A)
- C(A) is correct but (R) is not correct
- D(A) is not correct but (R) is correct
Correct answer
B. Both (A) and (R) are correct but (R) is not the correct explanation of (A)
Step-by-step solution
Assertion (A) is correct because glucagon is a peptide hormone. Peptide hormones are lipid-insoluble and cannot cross the cell membrane, so they interact with membrane-bound receptors and do not enter the target cells. Reason (R) is correct because the primary function of glucagon is to increase blood glucose levels by acting on hepatocytes to stimulate glycogenolysis and gluconeogenesis. However, Reason (R) does not explain Assertion (A). The correct explanation for Assertion (A) is the chemical nature of glucagon