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NEET2026BiologyChapterActual

A researcher is observing a skeletal muscle myofibril under an electron microscope. When the muscle is stimulated to undergo maximal contraction, which of the following structural changes will be observed?

Options

  1. AThe distance between two consecutive Z-lines increases.
  2. BThe central clear zone of the thick filaments completely vanishes.
  3. CThe thick filaments actively slide outward over the thin filaments.
  4. DThe anisotropic bands undergo a significant reduction in their length.

Correct answer

B. The central clear zone of the thick filaments completely vanishes.

Step-by-step solution

During muscle contraction, according to the sliding filament theory, thin filaments (actin) slide inward over thick filaments (myosin) towards the center of the sarcomere. This inward sliding pulls the Z-lines closer together, decreasing the distance between two consecutive Z-lines and shortening the sarcomere. The H-zone is the central clear zone of the A-band that contains only thick filaments. During maximal contraction, the thin filaments slide inward to such an extent that they overlap in the center, causing t

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