NEET2026BiologyChapterActual
In clinical practice, patients receiving organ transplants such as a kidney or liver must take immunosuppressants for their entire lives. These drugs are primarily administered to suppress the activity of which of the following?
Options
- AB-lymphocytes that generate a humoral immune response
- BT-lymphocytes that mediate a cell-mediated immune response
- CPolymorphonuclear leukocytes that provide cellular barriers
- DMast cells that trigger allergic inflammatory responses
Correct answer
B. T-lymphocytes that mediate a cell-mediated immune response
Step-by-step solution
Organ transplantation often faces the risk of graft rejection by the recipient's immune system. The body is able to differentiate between 'self' and 'non-self', and the cell-mediated immune response is primarily responsible for graft rejection. T-lymphocytes are the key cells that mediate this cell-mediated immunity. They recognize the transplanted organ as foreign and mount an immune attack against it. To prevent this rejection, patients must take immunosuppressant drugs (such as cyclosporine A) for their entire l