Arrange the following layers/regions of a mature human ovum in the correct sequence from the innermost to the outermost: A. Layer that undergoes changes to block polyspermy B. Cellular layer of corona radiata C. Perivitelline space D. Plasma membrane Choose the correct answer from the options given below:

Step-by-step solution

The layers of a mature human ovum from the innermost to the outermost are as follows: 1. Plasma membrane (D): The innermost boundary enclosing the oocyte cytoplasm (oolemma). 2. Perivitelline space (C): The narrow space located between the plasma membrane and the zona pellucida. 3. Zona pellucida (A): The acellular glycoprotein layer outside the perivitelline space. During fertilization, cortical granules release their contents into the perivitelline space, causing changes in the zona pellucida (zona reaction) to b