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MHT CET 202625 AprilMorning Shift
Exam
MHT CET
Year
2026
Date
25 April
Shift
Morning Shift
Subject
Biology
Chapter
Molecular Basis of Inheritance

MHT CET 2026 · 25 April · Morning Shift · Biology · Molecular Basis of Inheritance

During replication of DNA, formation of new strand takes place...

During replication of DNA, formation of new strand takes place ____________.

Options

  1. Ain 5′→3′5'\rightarrow3' direction on the leading template while in 3′→5′3'\rightarrow5' direction on the lagging template.
  2. Bin 5′→3′5'\rightarrow3' direction on the both the templates.
  3. Cin 3′→5′3'\rightarrow5' direction on the both the templates.
  4. Din 3′→5′3'\rightarrow5' direction on the leading template while 5′→3′5'\rightarrow3' direction on the lagging template.

Correct answer

B. in 5′→3′5'\rightarrow3' direction on the both the templates.

Step-by-step solution

DNA polymerase catalyzes the polymerization of deoxynucleotides only in one direction, which is 5′→3′5'\rightarrow3'.

Therefore, during DNA replication, the formation of the new strand always takes place in the 5′→3′5'\rightarrow3' direction on both the leading and lagging templates.

On the leading strand, the synthesis is continuous, while on the lagging strand, it is discontinuous (forming Okazaki fragments), but the direction of synthesis remains 5′→3′5'\rightarrow3' for both.

Answer: in 5′→3′5'\rightarrow3' direction on the both the templates.
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