MHT CET 202624 AprilMorning Shift
- Exam
- MHT CET
- Year
- 2026
- Date
- 24 April
- Shift
- Morning Shift
- Subject
- Biology
- Chapter
- Molecular Basis of Inheritance
MHT CET 2026 · 24 April · Morning Shift · Biology · Molecular Basis of Inheritance
In protein synthesis, during elongation of a polypeptide chain, the...
In protein synthesis, during elongation of a polypeptide chain, the charged tRNA carrying the aminoacid is received at ___ site and uncharged tRNA is released from ___ site of the ribosome respectively.
Options
- A'A' and 'P'
- B'P' and 'A'
- C'A' and 'E'
- D'P' and 'E'
Correct answer
C. 'A' and 'E'
Step-by-step solution
During the elongation phase of protein synthesis, the ribosome has three specific sites for tRNA binding: the A (aminoacyl) site, the P (peptidyl) site, and the E (exit) site.
The incoming charged tRNA (aminoacyl-tRNA) carrying the next amino acid to be added to the polypeptide chain binds to the A site.
After the peptide bond is formed, the ribosome translocates, shifting the uncharged tRNA to the E site, from where it is released into the cytoplasm.
Therefore, the charged tRNA is received at the 'A' site and the uncharged tRNA is released from the 'E' site.
Answer: 'A' and 'E'
The incoming charged tRNA (aminoacyl-tRNA) carrying the next amino acid to be added to the polypeptide chain binds to the A site.
After the peptide bond is formed, the ribosome translocates, shifting the uncharged tRNA to the E site, from where it is released into the cytoplasm.
Therefore, the charged tRNA is received at the 'A' site and the uncharged tRNA is released from the 'E' site.
Answer: 'A' and 'E'