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MHT CET 202624 AprilMorning Shift
Exam
MHT CET
Year
2026
Date
24 April
Shift
Morning Shift
Subject
Biology
Chapter
Molecular Basis of Inheritance

MHT CET 2026 · 24 April · Morning Shift · Biology · Molecular Basis of Inheritance

Along with Histone like DNA binding proteins which enzyme maintains...

Along with Histone like DNA binding proteins which enzyme maintains supercoiled state in packaging of DNA in prokaryotes?

Options

  1. ADNA polymerase and RNA primase
  2. BDNA ligase and helicase
  3. CDNA gyrase and topoisomerase I
  4. DPhosphorylase and RNA polymerase

Correct answer

C. DNA gyrase and topoisomerase I

Step-by-step solution

In prokaryotes, the DNA is organized into large loops held by histone-like DNA binding proteins. The supercoiled state of the circular DNA is maintained by the enzymes DNA gyrase (a type of topoisomerase II) and topoisomerase I.

DNA gyrase introduces negative supercoils into the DNA, whereas topoisomerase I relaxes them. Together, they balance and maintain the required supercoiled state for compact packaging of the nucleoid.

Answer: DNA gyrase and topoisomerase I
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