MHT CET Medical202622 April 2026Evening ShiftBiologyMolecular Basis of InheritanceActual
Which one of the following experiments by Griffith with Streptococcus pneumoniae , resulted in the death of mice due to pneumonia?
Options
- AMice injected only with heat killed S strain.
- BMice injected with live R strain and heat killed S strain.
- CMice injected with heat killed R as well as S strains.
- DMice injected only with heat killed R strain.
Correct answer
B. Mice injected with live R strain and heat killed S strain.
Step-by-step solution
Frederick Griffith conducted a series of experiments with Streptococcus pneumoniae to demonstrate bacterial transformation. When mice were injected with the live S strain (virulent), they died from pneumonia. When injected with the live R strain (non-virulent), they survived. When injected with the heat-killed S strain, they survived. When injected with a mixture of live R strain and heat-killed S strain, the mice died. This occurred because some transforming principle from the heat-killed S strain enabled the live