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MHT CET Medical202622 April 2026Evening ShiftBiologyMolecular Basis of InheritanceActual

Which one of the following experiments by Griffith with Streptococcus pneumoniae , resulted in the death of mice due to pneumonia?

Options

  1. AMice injected only with heat killed S strain.
  2. BMice injected with live R strain and heat killed S strain.
  3. CMice injected with heat killed R as well as S strains.
  4. DMice injected only with heat killed R strain.

Correct answer

B. Mice injected with live R strain and heat killed S strain.

Step-by-step solution

Frederick Griffith conducted a series of experiments with Streptococcus pneumoniae to demonstrate bacterial transformation. When mice were injected with the live S strain (virulent), they died from pneumonia. When injected with the live R strain (non-virulent), they survived. When injected with the heat-killed S strain, they survived. When injected with a mixture of live R strain and heat-killed S strain, the mice died. This occurred because some transforming principle from the heat-killed S strain enabled the live

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