MHT CET Medical202624 April 2026Evening ShiftBiologyPrinciples of Inheritance and VariationActual
Match the disorders in List I with their causes in List II and choose the correct option. List I List II (A) Thalassemia. (I) non-disjunction of sex chromosomes. (B) Sickle-cell anaemia. (II) non-disjuction of 21st pair of chromosomes. (C) Turner's Syndrome. (III) Synthesising few globin molecules. (D) Down's Syndrome. (IV) synthesising an incorrectly functional globin.
Options
- A(A) - (I), (B) - (II), (C) - (III), (D) - (IV).
- B(A) - (II), (B) - (IV), (C) - (I), (D) - (III).
- C(A) - (I), (B) - (II), (C) - (IV), (D) - (III).
- D(A) - (III), (B) - (IV), (C) - (I), (D) - (II).
Correct answer
D. (A) - (III), (B) - (IV), (C) - (I), (D) - (II).
Step-by-step solution
Thalassemia is a quantitative blood disorder that results in the synthesis of too few globin molecules. Thus, (A) matches (III). Sickle-cell anaemia is a qualitative blood disorder that results in the synthesis of an incorrectly functioning globin molecule. Thus, (B) matches (IV). Turner's Syndrome is caused by the absence of one of the X chromosomes ( 45 with X0 ), which occurs due to the non-disjunction of sex chromosomes during gametogenesis. Thus, (C) matches (I). Down's Syndrome is caused by the presence of an