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MHT CET 202623 AprilEvening Shift
Exam
MHT CET
Year
2026
Date
23 April
Shift
Evening Shift
Subject
Biology
Chapter
Principles of Inheritance and Variation

MHT CET 2026 · 23 April · Evening Shift · Biology · Principles of Inheritance and Variation

Which of the following statements are CORRECT? Statement (I):...

Which of the following statements are CORRECT?
Statement (I): Thalassemia is an autosomal, inherited recessive disease.
Statement (II): Haemoglobin molecule is made up of four polypeptide chain - 2α2\alpha and 2β2\beta chains
Statement (III): The synthesis of α\alpha-chain are controlled by HBA 1 and HBA2 on chromosome 11
Statement (IV): The synthesis of β\beta chain is controlled by single gene (HBB) on chromosome 16.

Options

  1. AAll statements are correct
  2. BAll statements are incorrect
  3. CStatement (I) and (II) are correct while (III) and (IV) are incorrect
  4. DStatement (III) and (IV) are correct while (I) and (II) are incorrect

Correct answer

C. Statement (I) and (II) are correct while (III) and (IV) are incorrect

Step-by-step solution

Statement (I) is correct as Thalassemia is an autosomal recessive inherited disease.

Statement (II) is correct as the adult haemoglobin molecule consists of four polypeptide chains, which are two α\alpha and two β\beta chains.

Statement (III) is incorrect because the synthesis of the α\alpha-chain is controlled by two closely linked genes, HBA1 and HBA2, located on chromosome 16, not chromosome 11.

Statement (IV) is incorrect because the synthesis of the β\beta-chain is controlled by a single gene, HBB, located on chromosome 11, not chromosome 16.

Therefore, Statements (I) and (II) are correct while (III) and (IV) are incorrect.

Answer: Statement (I) and (II) are correct while (III) and (IV) are incorrect
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