MHT CET Medical202623 April 2026Evening ShiftBiologyPrinciples of Inheritance and VariationActual
Which of the following statements are CORRECT? Statement (I): Thalassemia is an autosomal, inherited recessive disease. Statement (II): Haemoglobin molecule is made up of four polypeptide chain - 2 and 2 chains Statement (III): The synthesis of -chain are controlled by HBA 1 and HBA2 on chromosome 11 Statement (IV): The synthesis of chain is controlled by single gene (HBB) on chromosome 16.
Options
- AAll statements are correct
- BAll statements are incorrect
- CStatement (I) and (II) are correct while (III) and (IV) are incorrect
- DStatement (III) and (IV) are correct while (I) and (II) are incorrect
Correct answer
C. Statement (I) and (II) are correct while (III) and (IV) are incorrect
Step-by-step solution
Statement (I) is correct as Thalassemia is an autosomal recessive inherited disease. Statement (II) is correct as the adult haemoglobin molecule consists of four polypeptide chains, which are two and two chains. Statement (III) is incorrect because the synthesis of the -chain is controlled by two closely linked genes, HBA1 and HBA2, located on chromosome 16, not chromosome 11. Statement (IV) is incorrect because the synthesis of the -chain is controlled by a single gene, HBB, located on chromosome 11, not chromosom