MHT CET 202624 AprilMorning Shift
- Exam
- MHT CET
- Year
- 2026
- Date
- 24 April
- Shift
- Morning Shift
- Subject
- Biology
- Chapter
- Principles of Inheritance and Variation
MHT CET 2026 · 24 April · Morning Shift · Biology · Principles of Inheritance and Variation
Which one of the following disorder shows symptoms of excess of...
Which one of the following disorder shows symptoms of excess of phenylalanine in urine of humans?
Options
- AAlbuminuria
- BGout arthritis
- CUrinary tract infection
- DPhenylketonuria
Correct answer
D. Phenylketonuria
Step-by-step solution
Phenylketonuria is an inborn error of metabolism inherited as an autosomal recessive trait.
The affected individual lacks an enzyme called phenylalanine hydroxylase that converts the amino acid phenylalanine into tyrosine.
As a result, phenylalanine accumulates and gets converted into phenylpyruvic acid and other derivatives.
Accumulation of these in the brain results in mental retardation. These are also excreted through urine because of their poor absorption by the kidney.
Answer: Phenylketonuria
The affected individual lacks an enzyme called phenylalanine hydroxylase that converts the amino acid phenylalanine into tyrosine.
As a result, phenylalanine accumulates and gets converted into phenylpyruvic acid and other derivatives.
Accumulation of these in the brain results in mental retardation. These are also excreted through urine because of their poor absorption by the kidney.
Answer: Phenylketonuria