MHT CET Medical202621 April 2026Evening ShiftBiologyPrinciples of Inheritance and VariationActual
Which one of the following is a mismatch?
Options
- ADown's syndrome - Autosomal aneuploids
- BKlinefelter's syndrome - XO complement
- CHaemophilia - Sex linked
- DTurner's syndrome - Females with poor sexual development
Correct answer
B. Klinefelter's syndrome - XO complement
Step-by-step solution
Down's syndrome is caused by the presence of an additional copy of chromosome number 21 (trisomy of 21), which is an autosomal aneuploidy. Klinefelter's syndrome is caused by the presence of an additional copy of the X-chromosome resulting in a karyotype of 47, XXY. The XO complement is seen in Turner's syndrome. Thus, this is a mismatch. Haemophilia is a sex-linked recessive disease, which shows its transmission from an unaffected carrier female to some of the male progeny. Turner's syndrome is caused by the absen