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MHT CET Medical202623 April 2026Evening ShiftBiologyPrinciples of Inheritance and VariationActual

Read the following statement with respect to Phenylketonuria (PKU) and select the correct option. (A). It is an inborn disorder caused due to dominant gene. (B). When recessive genes are present in homozygous condition, Phenylalanine hydroxylase enzyme is not produced. (C). This enzyme is essential for conversion of amino acid tyrosine into phenylanine

Options

  1. AStatement A, B are correct and C is incorrect
  2. BStatement B is correct and A and C are incorrect
  3. CStatement A, B and C are incorrect
  4. DStatement A, B and C are correct

Correct answer

B. Statement B is correct and A and C are incorrect

Step-by-step solution

Phenylketonuria (PKU) is an inborn error of metabolism that is inherited as an autosomal recessive trait. Thus, statement A is incorrect. The affected individual lacks the enzyme phenylalanine hydroxylase, which is not produced when the recessive genes are present in a homozygous condition. Thus, statement B is correct. The enzyme phenylalanine hydroxylase is essential for the conversion of the amino acid phenylalanine into tyrosine, not the other way around. Thus, statement C is incorrect. Therefore, statement B i

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