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NEET2023ZoologyBiotechnology and Its ApplicationsActual

Select incorrect statement, regarding chemical structure of insulin.

Options

  1. AC-peptide is not present in mature insulin molecule.
  2. BPolypeptide chains A and B are linked by disulphide bridges.
  3. CMature insulin molecule consists of three polypeptide chains - A, B and C.
  4. DInsulin is synthesized as prohormone which contains extra stretch of C-peptide.

Correct answer

C. Mature insulin molecule consists of three polypeptide chains - A, B and C.

Step-by-step solution

Option (3) is the answer because mature insulin does not contain C-peptide chain which is removed during maturation of pro-insulin into insulin. So, it contains only two polypeptide chains A and B . Option (1) is not the answer because C-peptide is absent in mature insulin molecule. Option (2) is not the answer because polypeptide chains A and B are linked disulphide bridges. Option (4) is not the answer because an extra stretch C-peptide is not present in mature insulin but present in pro-insulin.

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