Human insulin is being commercially produced from a transgenic...

In 1983 an American company Eli Lily produced the first genetically engineered insulin by first synthesizing two DNA sequences corresponding to $A$ and $B$ insulin chains. The two DNA sequences or genes were made to fuse with plasmids of Escherichia coli and later allowed to form insulin chains. Rhizobium is a Gram negative, aerobic, motile, non-spore forming symbiotic nitrogen-fixing bacterium. It can fix nitrogen only when they are present inside the root nodules. Mycobacterium tuberculosis causes tuberculosis in man. It is an acute bacterial infection of the lungs, lymph and meninges. Saccharomyces cerevisiae is known as Baker's yeast and Saccharomyces ellipsoidens is wine yeast and these are used in baking and brewing industry respectively.