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NEET
Exam
NEET
Subject
Zoology
Chapter
Biotechnology - Principles and Processes

NEET · Zoology · Biotechnology - Principles and Processes

What was the first instance of recombinant DNA construction made of?

What was the first instance of recombinant DNA construction made of?

Options

  1. AA piece of cut DNA from a plasmid responsible for antibiotic resistance
  2. BA type of bacterium
  3. CA viral particle
  4. DAntibiotic resistance gene

Correct answer

A. A piece of cut DNA from a plasmid responsible for antibiotic resistance

Step-by-step solution

The construction of the first recombinant DNA emerged from the possibility of linking a gene encoding antibiotic resistance with a native plasmid (autonomously replicating circular extra-chromosomal DNA) of Salmonella typhimurium. Stanley Cohen and Herbert Boyer accomplished this in 1972 by isolating the antibiotic resistance gene by cutting out a piece of DNA from a plasmid which was responsible for conferring antibiotic resistance

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