NEETZoologyBiotechnology - Principles and Processes
Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): Plasmids are widely used as cloning vectors in recombinant DNA technology. Reason (R): Plasmids are extrachromosomal DNA molecules that can replicate autonomously independent of the control of chromosomal DNA. In the light of the above statements, choose the most appropriate answer from the options
Options
- ABoth (A) and (R) are correct and (R) is the correct explanation of (A)
- BBoth (A) and (R) are correct but (R) is not the correct explanation of (A)
- C(A) is correct but (R) is incorrect
- D(A) is incorrect but (R) is correct
Correct answer
A. Both (A) and (R) are correct and (R) is the correct explanation of (A)
Step-by-step solution
Assertion (A) is correct because plasmids are extensively used as cloning vectors to carry and multiply alien DNA fragments in host cells. Reason (R) is also correct and provides the valid explanation for the Assertion. Plasmids have their own origin of replication and can replicate autonomously independent of the host chromosomal DNA. Because of this property, when an alien piece of DNA is linked to a plasmid, it is replicated along with the plasmid, allowing the amplification of the alien DNA. Thus, both (A) and