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NEETZoologyBiotechnology - Principles and Processes

Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): A naked piece of alien DNA transferred into a host cell usually fails to multiply itself independently in the progeny cells. Reason (R): The host cell's DNA polymerase can initiate replication of the alien DNA even in the absence of an origin of replication (ori) sequence. In the light of the above

Options

  1. ABoth (A) and (R) are correct and (R) is the correct explanation of (A)
  2. BBoth (A) and (R) are correct but (R) is not the correct explanation of (A)
  3. C(A) is correct but (R) is not correct
  4. D(A) is not correct but (R) is correct

Correct answer

C. (A) is correct but (R) is not correct

Step-by-step solution

Assertion (A) is correct because a naked piece of alien DNA lacking an origin of replication cannot multiply independently in the host cell. It must integrate into the host's genome to be replicated and inherited by progeny cells. Reason (R) is incorrect because DNA polymerase cannot initiate replication randomly from any point on a DNA molecule. Replication must start at a specific DNA sequence called the origin of replication (ori). Without this specific sequence, the alien DNA cannot be replicated by the host's

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