NEETZoologyBiotechnology - Principles and Processes
Match List-I with List-II regarding the agents used in the isolation of genetic material: List-I List-II (A) Lysozyme (I) Precipitates pure DNA (B) Protease (II) Breaks bacterial cell wall (C) Ribonuclease (III) Degrades RNA (D) Chilled ethanol (IV) Degrades histones Choose the correct answer from the options given below:
Options
- A(A)-(II), (B)-(III), (C)-(IV), (D)-(I)
- B(A)-(II), (B)-(IV), (C)-(I), (D)-(III)
- C(A)-(I), (B)-(IV), (C)-(III), (D)-(II)
- D(A)-(II), (B)-(IV), (C)-(III), (D)-(I)
Correct answer
D. (A)-(II), (B)-(IV), (C)-(III), (D)-(I)
Step-by-step solution
During the isolation of genetic material in recombinant DNA technology, different enzymes and chemicals have specific roles. Lysozyme is used to break open bacterial cells to release their intracellular contents. Protease is used to degrade proteins, such as histones, that are intertwined with the DNA. Ribonuclease (RNase) specifically degrades RNA molecules present in the mixture. Chilled ethanol is added at the end of the purification process to precipitate out the purified DNA as fine threads. Therefore, the cor