NEETZoologyBiotechnology - Principles and Processes
Match the steps of Polymerase Chain Reaction (PCR) given in List-I with their corresponding key events in List-II. List-I List-II A. Denaturation I. Binding of primers to complementary sequences B. Annealing II. Separation of double-stranded DNA C. Extension III. Addition of nucleotides to the primer Choose the correct answer from the options given below:
Options
- AA-II, B-III, C-I
- BA-I, B-II, C-III
- CA-II, B-I, C-III
- DA-III, B-I, C-II
Correct answer
C. A-II, B-I, C-III
Step-by-step solution
Polymerase Chain Reaction (PCR) completes one cycle in three steps: 1. Denaturation: The double-stranded template DNA is heated to a high temperature, causing the two strands to separate. 2. Annealing: The temperature is lowered to allow short oligonucleotide primers to bind to their complementary sequences on the single-stranded DNA. 3. Extension: Taq DNA polymerase adds deoxynucleotides to the primers, extending the new DNA strand. Therefore, the correct matching is A-II, B-I, C-III. Answer: A-II, B-I, C-III