NEET2018ZoologyBiotechnology - Principles and ProcessesActual
Which of the following is commonly used as a vector for introducing a DNA fragment in human lymphocytes?
Options
- Aλ phage
- BTi plasmid
- CRetrovirus
- DpBR 322
Correct answer
C. Retrovirus
Step-by-step solution
Usually, a retrovirus is used as a vector for introducing a DNA fragment in human cells. They have used as a vector in gene therapy to introduce the desired gene so as to replace the functioning of a defective gene Ex: Severe Combined Immune Deficiency (SCID) is a disease caused due to a defect in the gene for the enzyme adenosine deaminase. In gene therapy against it, lymphocytes are extracted from the bone marrow of the patient. These are grown in a culture outside the body. A functional ADA rDNA, using a retrovi