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NEET2015ZoologyBiotechnology - Principles and ProcessesActual

The construction of the first recombinant DNA emerged from the possibility of linking a gene encoding antibiotic resistance with a native plasmid of

Options

  1. ASalmonella typhimurium
  2. BEscherichia coli
  3. CHaemophilus influenzae
  4. DBacillus thuringiensis

Correct answer

A. Salmonella typhimurium

Step-by-step solution

The construction of the first recombinant DNA emerged from the possibility of linking a gene encoding antibiotic resistance with a native plasmid (autonomously replicating circular extra-chromosomal DNA) of Salmonella typhimurium. Stanley Cohen and Herbert Boyer accomplished this in 1972 by isolating the antibiotic resistance gene by cutting out a piece of DNA from a plasmid which was responsible for conferring antibiotic resistance.

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